BIO-11006 acetate salt( —— )

Catalog No. M30156 CAS No. ——

BIO-11006 acetate salt is a polyglycosylated alanine rich C kinase substrate (MARCKS) inhibitor similar to MANS peptides.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

BIO-11006 acetate salt
Note

Research use only, not for human use.
Brief Description

BIO-11006 acetate salt is a polyglycosylated alanine rich C kinase substrate (MARCKS) inhibitor similar to MANS peptides.
Description

BIO-11006 acetate salt is a polyglycosylated alanine rich C kinase substrate (MARCKS) inhibitor similar to MANS peptides.(In Vivo):Inhaled, aerosolized BIO-11006 attenuates LPS-induced neutrophil influx into the lung, activation of NF-κB, and expression of the proinflammatory cytokines, KC and TNF-α, and thus reverses the development of lung injury in mice instilled intratracheally with LPS.
In Vitro

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In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Myristoylated alanine-rich C kise substrate
Research Area

——
Indication

——

Chemical Information

CAS Number

——
Formula Weight

1110.22
Molecular Formula

C48H79N13O17
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

Yin Q, et al. An Inhaled Inhibitor of Myristoylated Alanine-Rich C Kinase Substrate Reverses LPS-Induced Acute Lung Injury in Mice. Am J Respir Cell Mol Biol. 2016 Nov;55(5):617-622.

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