FC131 TFA (606968-52-9 free base)( —— )

Catalog No. M30047 CAS No. ——

FC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

FC131 TFA (606968-52-9 free base)
Note

Research use only, not for human use.
Brief Description

FC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.
Description

FC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Autophagy
Target

CXCR
Recptor

IC50: 4.5 nM ([125I]-SDF-1-CXCR4)
Research Area

——
Indication

——

Chemical Information

CAS Number

——
Formula Weight

843.85
Molecular Formula

C38H48F3N11O8
Purity

>98% (HPLC)
Solubility

DMSO : 250 mg/mL (296.26 mM; Need ultrasonic)
SMILES

——
Chemical Name

Sequence:{2-Naph-Ala}-{Gly}-{Tyr}-{Arg}-{Arg}

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.

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