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G3-C12 TFA (848301-94-0 free base)
CAS No. ——
G3-C12 TFA (848301-94-0 free base)( —— )
Catalog No. M29993 CAS No. ——
G3-C12 TFA Salt is a specific galectin-3 binding peptide with Ksubdsub of 88 nM and shows anticancer activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameG3-C12 TFA (848301-94-0 free base)
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NoteResearch use only, not for human use.
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Brief DescriptionG3-C12 TFA Salt is a specific galectin-3 binding peptide with Ksubdsub of 88 nM and shows anticancer activity.
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DescriptionG3-C12 TFA Salt is a specific galectin-3 binding peptide with Ksubdsub of 88 nM and shows anticancer activity.(In Vitro):G3-C12 (TFA) is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 (TFA) bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorKd: 88 nM (Galectin-3)
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight1873
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Molecular FormulaC74H115N23O23S2.C2HF3O2
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Purity>98% (HPLC)
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SolubilityH2O : ≥ 50 mg/mL (26.70 mM)
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Kopansky E, et al. Peptide-directed HPMA copolymer-doxorubicin conjugates as targeted therapeutics for colorectal cancer. J Drug Target. 2011 Dec;19(10):933-43.
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