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β-Amyloid 22-35
CAS No. 144189-71-9
β-Amyloid 22-35( Amyloid β-Protein (22-35) )
Catalog No. M29924 CAS No. 144189-71-9
β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 206 | Get Quote |
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| 10MG | 356 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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Biological Information
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Product Nameβ-Amyloid 22-35
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NoteResearch use only, not for human use.
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Brief Descriptionβ-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide.
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Descriptionβ-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide. (In Vitro):β-Amyloid (22-35) shows significant cytotoxicity on the rat hippocampal neurons at 40 μg/mL, but exhibits no cytotoxic effect on the glial cells.
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In Vitroβ-Amyloid 22-35 shows significant cytotoxicity on the rat hippocampal neurons at 40 μg/mL, but exhibits no cytotoxic effect on the glial cells.
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In Vivo——
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SynonymsAmyloid β-Protein (22-35)
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PathwayMembrane Transporter/Ion Channel
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TargetBeta Amyloid
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RecptorAmyloid-β
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Research Area——
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Indication——
Chemical Information
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CAS Number144189-71-9
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Formula Weight1403.62
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Molecular FormulaC59H102N16O21S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 1.85 mg/mL (1.32 mMu)
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SMILES——
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Chemical NameSequence:Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Fenlean
Fenlean (FLZ) is a tyrosine kinase Src inhibitor, a synthetic cyclic derivative of squamous amide from Annona glabra, with cytoprotective activity, which protects tyrosine hydroxylase function in a chronic MPTP/prostaglandin-type mouse model of Parkinson's disease.
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Hoechst 34580
Hoechst 34580, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.Hoechst 34580 is a good candidate for treating Alzheimer’s disease by inhibiting Aβ formation. 50 μM Aβ42 solutions co-incubated with 100, 25, 12.5, 3.125, 0.78, and 0.1, 0.01 μM Hoechst 34580 at 37 °C for 70 h. Hoechst 34580 can inhibit the aggregation of Aβ42 in a dose-dependent manner.
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β-Amyloid 31-35
β-Amyloid (31-35) is the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity. This synthetic peptide consists of amino acids 31 to 35 of beta amyloid protein.
