β-Casomorphin, bovine TFA
CAS No. ——
β-Casomorphin, bovine TFA( β-Casomorphin-7 (bovine) (TFA); Bovine β-casomorphin-7 TFA )
Catalog No. M29705 CAS No. ——
β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
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Biological Information
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Product Nameβ-Casomorphin, bovine TFA
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NoteResearch use only, not for human use.
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Brief Descriptionβ-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.
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Descriptionβ-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.(In Vitro):β-Casomorphin, bovine TFA (0.1μM; 30 minutes-24 hours) stimulates the secretion of mucin in DHE Cells after 8 h of treatment. β-Casomorphin, bovine TFA (0.1μM; 24 hours) induces an increase in rMuc2 and rMuc3 mRNA levels. β-Casomorphin, bovine TFA does not modify the expression of rMuc1, rMuc4, and rMuc5AC. β-Casomorphin, bovine TFA (0.1μM; 24 hours) stimulates MUC5AC expression and mucin Secretion in HT29-MTX Cells (human).(In Vivo):β-Casomorphin, bovine TFA (7.5×10 6 mol/day/kg ; i.g.; for 30 days) increases plasma insulin and decreased plasma glucagon of diabetic rats. β-Casomorphin, bovine TFA (7.5×10 6 mol/day/kg ; i.g.; for 30 days) alters the changes of SOD, GPx, T-AOC, MDA and H2O2 in the kidney of diabetic rats. β-Casomorphin, bovine TFA (7.5×10 6 mol/day/kg ; i.g.; for 30 days) reduces MDA (significantly) and H2O2 (non-significantly) level in the kidney compared to the diabetic rats. β-Casomorphin, bovine TFA (7.5×10 6 mol/day/kg ; i.g.; for 30 days) alleviates high glucose-induced decreasement in SOD and GPx activity, increasement in MDA contents in the NRK-52E cells.
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In Vitro——
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In Vivo——
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Synonymsβ-Casomorphin-7 (bovine) (TFA); Bovine β-casomorphin-7 TFA
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PathwayOthers
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TargetOther Targets
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RecptorIC50: 14 μM (Opioid receptor)
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight903.94
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Molecular FormulaC43H56F3N7O11
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:Tyr-Pro-Phe-Pro-Gly-Pro-Ile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Brantl V, et al. Opioid activities of beta-casomorphins. Life Sci. 1981 Apr 27;28(17):1903-9.
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