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BIBF 1202

CAS No. 894783-71-2

BIBF 1202( —— )

Catalog No. M29632 CAS No. 894783-71-2

BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BIBF 1202
  • Note
    Research use only, not for human use.
  • Brief Description
    BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).
  • Description
    BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).(In Vitro):BIBF 1202 is produced in the main metabolic pathway of BIBF 1120 by the cleavage of methyl esters. Then, the free carboxyl group of BIBF 1202 is glucuronidated to 1-O-acyl glucuronide .
  • In Vitro
    The major metabolic pathway for BIBF 1120 is methyl ester cleavage to BIBF 1202. Subsequently, the free carboxyl group of BIBF 1202 is glucuronidated to 1-O-acylglucuronide.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    VEGFR
  • Recptor
    VEGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    894783-71-2
  • Formula Weight
    525.609
  • Molecular Formula
    C30H31N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 45 mg/mL (85.62 mM)
  • SMILES
    CN(C(=O)CN1CCN(C)CC1)c1ccc(N\C(=C2/C(=O)Nc3cc(ccc23)C(O)=O)c2ccccc2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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