Iriflophenone

Research use only, not for human use.

Iriflophenone stimulates cells proliferation in MCF-7 and T-47D human breast cancer.

Iriflophenone stimulates cells proliferation in MCF-7 and T-47D human breast cancer.(In Vitro):2,2'-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity was used to evaluate the antioxidant capacity of the CPE. Experimental results concluded that ethanol concentration and solid-to-solvent ratio had significant effects (p<0.05) on the yields of polyphenol and antioxidant capacity. Extraction time had an insignificant influence on the recovery of EGCG, ECG and Iriflophenone 3-C-β-glucoside, as well as radical scavenging capacity from the CPE. The extraction parameters that exhibited maximum yields were 40% (v/v) ethanol, 1:60 (w/v) for 30 min where the TPC, TFC, TF, DPPH, EGCG, ECG and Iriflophenone 3-C-β-glucoside levels achieved were 183.5 mg GAE/g DW, 249.0 mg QE/g DW, 4.9 mg CE/g DW, 93.7%, 29.1 mg EGCG/g DW, 44.3 mg ECG/g DW and 39.9 mg Iriflophenone 3-C-β-glucoside/g DW respectively. The IC50 of the CPE was 24.6 mg/L.

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Endocrinology/Hormones

Estrogen Receptor/ERR

Estrogen Receptor/ERR

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52591-10-3

246.218

C13H10O5

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (1015.35 mM)

Oc1ccc(cc1)C(=O)c1c(O)cc(O)cc1O

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(-20℃)

With Ice Pack

≥ 2 years