(2S)-6-Prenylnaringenin

Research use only, not for human use.

6-Prenylnaringenin is an isomer of the potent phytoestrogen, 8-prenylnaringenin. 6-Prenylnaringenin is the most potent compound in the forebrain and acts as a positive allosteric modulator of GABAA at the α+β binding site.

6-Prenylnaringenin is an isomer of the potent phytoestrogen, 8-prenylnaringenin. 6-Prenylnaringenin is the most potent compound in the forebrain and acts as a positive allosteric modulator of GABAA at the α+β binding site.(In Vitro):In native GABAA receptors, 6-Prenylnaringenin potentiates GABA-induced displacement of [3H]EBOB binding in a concentration-dependent manner with IC50s of 3.7 μM. 6-Prenylnaringenin displays a modulatory activity at low micromolar concentrations.

(2S)-6-Prenylnaringenin (6-Prenylnaringenin) displays a modulatory activity at low micromolar concentrations. (2S)-6-Prenylnaringenin potentiates GABA-induced displacement of [3H]EBOB binding in a concentration-dependent manner where the IC50 value for this potentiation in native GABAA receptors is 3.7 μM, respectively.

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6-Prenylnaringenin | (2S)-6-Prenylnaringenin | 6-PN

Others

Other Targets

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68236-13-5

340.375

C20H20O5

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (293.80 mM)

CC(C)=CCc1c(O)cc2O[C@@H](CC(=O)c2c1O)c1ccc(O)cc1

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(-20℃)

With Ice Pack

≥ 2 years