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GLL 398
CAS No. 2077980-80-2
GLL 398( —— )
Catalog No. M29017 CAS No. 2077980-80-2
GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 393 | Get Quote |
|
| 10MG | 590 | Get Quote |
|
| 25MG | 1060 | Get Quote |
|
| 50MG | 1591 | Get Quote |
|
| 100MG | 2387 | Get Quote |
|
| 200MG | 3580 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGLL 398
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NoteResearch use only, not for human use.
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Brief DescriptionGLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.
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DescriptionGLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.(In Vitro):GLL398 exhibits a strong dose-dependent binding profile for the estrogen receptor with a Y537S point mutation with an IC50 of 29.5 nM.
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In VitroGLL398 is a boron-modified GW5638 analog.
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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RecptorEstrogen Receptor/ERR
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Research Area——
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Indication——
Chemical Information
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CAS Number2077980-80-2
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Formula Weight398.26
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Molecular FormulaC25H23BO4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (627.73 mM)
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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