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JAMM protein inhibitor 2?

CAS No. 848249-35-4

JAMM protein inhibitor 2?( Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]- )

Catalog No. M28957 CAS No. 848249-35-4

JAMM protein inhibitor 2 is an inhibitor of JAMM protease and can be used for anticancer studies. The IC50s are 10 μM, 46 μM, and 89 μM for thrombin, Rpn11, and MMP2, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 37 In Stock
5MG 103 In Stock
10MG 167 In Stock
25MG 353 In Stock
50MG 510 In Stock
100MG 724 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    JAMM protein inhibitor 2?
  • Note
    Research use only, not for human use.
  • Brief Description
    JAMM protein inhibitor 2 is an inhibitor of JAMM protease and can be used for anticancer studies. The IC50s are 10 μM, 46 μM, and 89 μM for thrombin, Rpn11, and MMP2, respectively.
  • Description
    JAMM protein inhibitor 2 is an inhibitor of JAMM protease and can be used for anticancer studies. The IC50s are 10 μM, 46 μM, and 89 μM for thrombin, Rpn11, and MMP2, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    EGFR|Beta Amyloid
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    848249-35-4
  • Formula Weight
    338.451
  • Molecular Formula
    C21H26N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 14.71 mg/mL (43.46 mM)
  • SMILES
    CCc1ccccc1OCC(=O)Nc1ccc(cc1C)N1CCCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Buchdunger E, et al. 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2334-8.
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