Cart
sales@molnova.com
Elevenostat
CAS No. 1454902-97-6
Elevenostat( JB3-22 )
Catalog No. M28876 CAS No. 1454902-97-6
Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
|
| 5MG | 37 | In Stock |
|
| 10MG | 61 | In Stock |
|
| 25MG | 116 | In Stock |
|
| 50MG | 183 | In Stock |
|
| 100MG | 341 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameElevenostat
-
NoteResearch use only, not for human use.
-
Brief DescriptionElevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 μM.
-
DescriptionElevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 μM.(In Vitro):Elevenostat induced cell death in MM cell lines.(In Vivo):Elevenostat produced similar anti-MM activity in vivo, improving survival among mice inoculated with 5TGM1 MM cells.
-
In Vitro——
-
In Vivo——
-
SynonymsJB3-22
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
RecptorTelomerase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1454902-97-6
-
Formula Weight315.32
-
Molecular FormulaC16H17N3O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (792.85 mM)
-
SMILESCOc(cccc1)c1NC(NCc(cc1)ccc1C(NO)=O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Fleming AM, et al. Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5'-Untranslated Regions. Biochemistry. 2018 Feb 13;57(6):991-1002.
molnova catalog
related products
-
BRD3308
BRD3308 is a potent, selective HDAC3 inhibitor with IC50 of 54 nM.
-
T247
A potent and selective HDAC3 inhibitor with IC50 of 0.24 uM, >75-fold selectivity over HDAC1 and no activity against HDAC4/6/8.
-
LAQ824
LAQ824 (Dacinostat) is a novel HDAC inhibitor with IC50 of 32 nM and is known to activate the p21 promoter.
