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Elevenostat

CAS No. 1454902-97-6

Elevenostat( JB3-22 )

Catalog No. M28876 CAS No. 1454902-97-6

Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 41 In Stock
5MG 37 In Stock
10MG 61 In Stock
25MG 116 In Stock
50MG 183 In Stock
100MG 341 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Elevenostat
  • Note
    Research use only, not for human use.
  • Brief Description
    Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 μM.
  • Description
    Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 μM.(In Vitro):Elevenostat induced cell death in MM cell lines.(In Vivo):Elevenostat produced similar anti-MM activity in vivo, improving survival among mice inoculated with 5TGM1 MM cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    JB3-22
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    Telomerase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1454902-97-6
  • Formula Weight
    315.32
  • Molecular Formula
    C16H17N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (792.85 mM)
  • SMILES
    COc(cccc1)c1NC(NCc(cc1)ccc1C(NO)=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fleming AM, et al. Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5'-Untranslated Regions. Biochemistry. 2018 Feb 13;57(6):991-1002.
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