Cart
sales@molnova.com
Home -
Products -
Cell Cycle/DNA Damage -
Nucleoside Antimetabolite/Analog -
2'-Fluoro-2'-Deoxyadenosine
2'-Fluoro-2'-Deoxyadenosine
CAS No. 64183-27-3
2'-Fluoro-2'-Deoxyadenosine( —— )
Catalog No. M28866 CAS No. 64183-27-3
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 37 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name2'-Fluoro-2'-Deoxyadenosine
-
NoteResearch use only, not for human use.
-
Brief Description2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).
-
Description2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors expressing E. coli PNP. 2'-Fluoro-2'-Deoxyadenosine can be used to synthesize 2'-deoxy-2'-fluoromodified oligonucleotides that can hybridize to RNA.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetNucleoside Antimetabolite/Analog
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number64183-27-3
-
Formula Weight269.236
-
Molecular FormulaC10H12FN5O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (185.71 mM)
-
SMILESNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Chatterjee A , Sarkar S , Saha S K . Acacetin 7- O-β- d-galactopyranoside from Chrysanthemum indicum[J]. Phytochemistry, 1981, 20(7):1760-1761.
molnova catalog
related products
-
DFP-10917
DFP-10917 (CNDAC, TAS-109) is a deoxycytidine analog with antitumor activity against various tumor cells.
-
Acelarin
A gemcitabine phosphoramidate prodrug that can overcome the key cancer resistance.
-
Sangivamycin
Sangivamycin is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of human cancers.
