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TNIK-IN-2
CAS No. 2754265-76-2
TNIK-IN-2( —— )
Catalog No. M28760 CAS No. 2754265-76-2
TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 180 | In Stock |
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| 5MG | 172 | In Stock |
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| 10MG | 275 | In Stock |
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| 25MG | 452 | In Stock |
|
| 50MG | 631 | In Stock |
|
| 100MG | 848 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTNIK-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionTNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.
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DescriptionTNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.(In Vitro):In HCT116 cells, the IC50 value was 31.26 μM for TNIK.
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In VitroTNIK-IN-2 (compound 1) inhibits TNIK, with an IC50 of 31.26 μM in HCT116 cells.
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In Vivo——
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Synonyms——
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PathwayWnt/Notch/Hedgehog
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TargetWnt/beta/catenin
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2754265-76-2
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Formula Weight373.4
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Molecular FormulaC22H19N3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESCOc1cccc(NC(c(ccc(-c2cnc3[nH]ccc3c2)c2)c2OC)=O)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kagenishi T, et al. MES Buffer Affects Arabidopsis Root Apex Zonation and Root Growth by Suppressing Superoxide Generation in Root Apex. Front Plant Sci. 2016;7:79. Published 2016 Feb 18.
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