TNIK-IN-2( —— )

Catalog No. M28760 CAS No. 2754265-76-2

TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

TNIK-IN-2
Note

Research use only, not for human use.
Brief Description

TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.
Description

TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.(In Vitro):In HCT116 cells, the IC50 value was 31.26 μM for TNIK.
In Vitro

TNIK-IN-2 (compound 1) inhibits TNIK, with an IC50 of 31.26 μM in HCT116 cells.
In Vivo

——
Synonyms

——
Pathway

Wnt/Notch/Hedgehog
Target

Wnt/beta/catenin
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

2754265-76-2
Formula Weight

373.4
Molecular Formula

C22H19N3O3
Purity

>98% (HPLC)
Solubility

——
SMILES

COc1cccc(NC(c(ccc(-c2cnc3[nH]ccc3c2)c2)c2OC)=O)c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Kagenishi T, et al. MES Buffer Affects Arabidopsis Root Apex Zonation and Root Growth by Suppressing Superoxide Generation in Root Apex. Front Plant Sci. 2016;7:79. Published 2016 Feb 18.

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