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AZ194
CAS No. 2241651-99-8
AZ194( CRMP2-Ubc9-NaV1.7 inhibitor 194 )
Catalog No. M28702 CAS No. 2241651-99-8
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 160 | Get Quote |
|
| 10MG | 260 | Get Quote |
|
| 25MG | 484 | Get Quote |
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| 50MG | 700 | Get Quote |
|
| 100MG | 981 | Get Quote |
|
| 500MG | 1962 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAZ194
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NoteResearch use only, not for human use.
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Brief DescriptionCRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
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DescriptionCRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
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In Vitro——
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In VivoAZ194 would provide pain relief in rat models of chemotherapy- and nerve injury- induced neuropathic pain. AZ194 (orally; at 2 and 10 mg/kg) restores mechanical sensitivity in animals with chemotherapy-induced and nerve injury-induced neuropathic nociception.AZ194 (10 mg/kg; ip; CD1 male mice) does not affect motor performance (open field). AZ194 synergizes with commonly used painkillers, engages NaV1.7-dependent endogenous opioid signaling.
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SynonymsCRMP2-Ubc9-NaV1.7 inhibitor 194
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2241651-99-8
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Formula Weight567.637
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Molecular FormulaC34H31F2N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (58.72 mM)
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SMILESCOc1cc(ccc1OCc1cccc(F)c1)C(=O)N1CCC(CC1)c1nc2ccccc2n1Cc1cccc(F)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dzierba CD, Hartz RA, Bronson JJ. Recent advances in corticotropin-releasing factor receptor antagonists. Annu Rep Med Chem. 2008;43:3–23.
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