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Pomalidomide 4'-PEG2-azide?
CAS No. 2271036-45-2
Pomalidomide 4'-PEG2-azide?( 4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione )
Catalog No. M28652 CAS No. 2271036-45-2
Pomalidomide 4'-PEG2-azide is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 40 | Get Quote |
|
| 10MG | 55 | Get Quote |
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| 25MG | 88 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NamePomalidomide 4'-PEG2-azide?
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NoteResearch use only, not for human use.
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Brief DescriptionPomalidomide 4'-PEG2-azide is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.
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DescriptionPomalidomide 4'-PEG2-azide is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs contain two different ligands, linked by a linker; one of them is a ligand for E3 ubiquitin ligase and the other is a ligand for the target protein.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2271036-45-2
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Formula Weight430.41
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Molecular FormulaC19H22N6O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (232.34 mM)
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SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCN=[N+]=[N-])=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Khare P, et al. Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells. AAPS J. 2021;24(1):8. Published 2021 Dec 6.
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