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Protein kinase inhibitor H-7

CAS No. 84477-87-2

Protein kinase inhibitor H-7( -(5-Isoquinolinylsulfonyl)-2-methylpiperazine | 5-(2-methylpiperazine-1-sulfonyl)isoquinoline )

Catalog No. M28552 CAS No. 84477-87-2

Protein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase inhibitor H-7 is also a cyclic nucleotide dependent protein kinase inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 78 Get Quote
25MG 123 Get Quote
50MG 176 Get Quote
100MG 257 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Protein kinase inhibitor H-7
  • Note
    Research use only, not for human use.
  • Brief Description
    Protein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase inhibitor H-7 is also a cyclic nucleotide dependent protein kinase inhibitor.
  • Description
    Protein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase inhibitor H-7 is also a cyclic nucleotide dependent protein kinase inhibitor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    -(5-Isoquinolinylsulfonyl)-2-methylpiperazine | 5-(2-methylpiperazine-1-sulfonyl)isoquinoline
  • Pathway
    Angiogenesis
  • Target
    PKC
  • Recptor
    Smoothened
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    84477-87-2
  • Formula Weight
    291.37
  • Molecular Formula
    C14H17N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (343.21 mM)
  • SMILES
    O=S(=O)(C1=CC=CC=2C=NC=CC21)N3CCNCC3C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang Y, et al. Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation. ACS Chem Biol. 2012 Jun 15;7(6):1040-8.
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