Fmoc-Lys-OH hydrochloride

CAS No. 139262-23-0

Fmoc-Lys-OH hydrochloride( —— )

Catalog No. M28362 CAS No. 139262-23-0

Fmoc-Lys-OH hydrochloride is a alkyl-chain-based PROTAC linker. Fmoc-Lys-OH hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Fmoc-Lys-OH hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Fmoc-Lys-OH hydrochloride is a alkyl-chain-based PROTAC linker. Fmoc-Lys-OH hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • Description
    Fmoc-Lys-OH hydrochloride is a alkyl-chain-based PROTAC linker. Fmoc-Lys-OH hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
  • In Vitro
    ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    NHE1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    139262-23-0
  • Formula Weight
    404.89
  • Molecular Formula
    C21H25ClN2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (308.73 mM)
  • SMILES
    Cl.NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Guzman-Perez A, et al. Discovery of zoniporide: a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility. Bioorg Med Chem Lett. 2001 Mar 26;11(6):803-7.
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