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Itaconate-alkyne

CAS No. 2454181-83-8

Itaconate-alkyne( ITalk )

Catalog No. M28361 CAS No. 2454181-83-8

Itaconate-alkyne is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its direct targets.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 169 In Stock
5MG 155 In Stock
10MG 250 In Stock
25MG 511 In Stock
50MG 724 In Stock
100MG 1014 In Stock
200MG Get Quote In Stock
500MG 2027 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Itaconate-alkyne
  • Note
    Research use only, not for human use.
  • Brief Description
    Itaconate-alkyne is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its direct targets.
  • Description
    Itaconate-alkyne is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its direct targets.(In Vitro):Itaconate-alkyne can capture itaconate targets including DNA damage-binding protein 1 (DDB1), Gelsolin (GSN), ATP-citrate synthase (ACLY) and Adenylate kinase 2 (AK2) in inflammatory macrophages.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ITalk
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2454181-83-8
  • Formula Weight
    238.28
  • Molecular Formula
    C13H18O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (1049.19 mM)
  • SMILES
    O=C(O)C(=C)CC(=O)OCCCCCCC#C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Daly JW, et al. Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow. Biochem Pharmacol. 1986 Aug 1;35(15):2467-81.
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