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Pomalidomide-PEG2-CO2H

CAS No. 2140807-17-4

Pomalidomide-PEG2-CO2H( Pomalidomide-PEG2-C2-acid | Pomalidomide 4'-PEG2-acid )

Catalog No. M28267 CAS No. 2140807-17-4

Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 140 In Stock
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Biological Information

  • Product Name
    Pomalidomide-PEG2-CO2H
  • Note
    Research use only, not for human use.
  • Brief Description
    Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
  • Description
    Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.(In Vitro):PROTACs contain two distinct ligands, one for the E3 ubiquitin ligase and the other for the target protein, linked by a linker.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Pomalidomide-PEG2-C2-acid | Pomalidomide 4'-PEG2-acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    EGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2140807-17-4
  • Formula Weight
    433.41
  • Molecular Formula
    C20H23N3O8
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 62.5 mg/mL (144.21 mM)
  • SMILES
    O=C(O)CCOCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fry DW, et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12022-7.
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