Cart
sales@molnova.com
Pomalidomide-PEG2-CO2H
CAS No. 2140807-17-4
Pomalidomide-PEG2-CO2H( Pomalidomide-PEG2-C2-acid | Pomalidomide 4'-PEG2-acid )
Catalog No. M28267 CAS No. 2140807-17-4
Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 54 | Get Quote |
|
| 10MG | 79 | Get Quote |
|
| 25MG | 132 | Get Quote |
|
| 50MG | 237 | Get Quote |
|
| 100MG | 347 | Get Quote |
|
| 200MG | 518 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePomalidomide-PEG2-CO2H
-
NoteResearch use only, not for human use.
-
Brief DescriptionPomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
-
DescriptionPomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.(In Vitro):PROTACs contain two distinct ligands, one for the E3 ubiquitin ligase and the other for the target protein, linked by a linker.
-
In Vitro——
-
In Vivo——
-
SynonymsPomalidomide-PEG2-C2-acid | Pomalidomide 4'-PEG2-acid
-
PathwayOthers
-
TargetOther Targets
-
RecptorEGFR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2140807-17-4
-
Formula Weight433.41
-
Molecular FormulaC20H23N3O8
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 62.5 mg/mL (144.21 mM)
-
SMILESO=C(O)CCOCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Fry DW, et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12022-7.
molnova catalog
related products
-
Deoxyribonuclease I
Deoxyribonuclease I (DNase I) is an enzyme commonly used to purify proteins with potential anti-inflammatory and anticancer activity and can be used to study bacterial and fungal infections.
-
Quin C1
Quin C1 is a selective and potent formylpeptide receptor 2 (FPR2/ALX) agonist with anti-inflammatory activity, inhibits neutrophil and lymphocyte production in BALF, and reduces the expression of TNF-α, IL-1β, KC, and TGF-β1.Quin C1 is used in the study of lung injury.
-
PACAP (6-38), human,...
PACAP (6-38), human, ovine, rat is a potent antagonist of PACAP 38. PACAP (6-38) is much more potent and selective than PACAP (6-27) in the inhibition of PACAP-27-stimulated pituitary adenylate cyclase.
