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Thalidomide-NH-C6-NH2 hydrochloride

CAS No. 2375194-37-7

Thalidomide-NH-C6-NH2 hydrochloride( Pomalidomide-C6-NH2 hydrochloride )

Catalog No. M28256 CAS No. 2375194-37-7

Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Thalidomide-NH-C6-NH2 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
  • Description
    Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    Pomalidomide-C6-NH2 hydrochloride
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ATPase|Calcium Channel|PAFR|Potassium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2375194-37-7
  • Formula Weight
    408.88
  • Molecular Formula
    C19H25ClN4O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.NCCCCCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Teng CM, et al. Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist--denudatin B, an isomer of kadsurenone. Thromb Res. 1990 Jul 1;59(1):121-30.
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