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Home - Products - Tyrosine Kinase - Ephrin Receptor - AWL-II-38.3

AWL-II-38.3

CAS No. 1135205-94-5

AWL-II-38.3( —— )

Catalog No. M28187 CAS No. 1135205-94-5

AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AWL-II-38.3
  • Note
    Research use only, not for human use.
  • Brief Description
    AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf.
  • Description
    AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf.(In Vitro):AWL-II-38.3 fits to LIMK2 and LIMK1 ATP-binding and substrate-binding pockets .
  • In Vitro
    AWL-II-38.3 fits to LIMK2 and LIMK1 ATP-binding and substrate-binding pockets.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Tyrosine Kinase
  • Target
    Ephrin Receptor
  • Recptor
    PEGs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1135205-94-5
  • Formula Weight
    469.42
  • Molecular Formula
    C23H18F3N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 66.67 mg/mL (142.03 mM)
  • SMILES
    CC1=CN(C=N1)C1=CC(=CC(=C1)C(F)(F)F)C(=O)NC1=CC=C(C)C(NC(=O)C2=CC=NO2)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
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