2,2,2-Trichloroethanol
CAS No. 115-20-8
2,2,2-Trichloroethanol( —— )
Catalog No. M28141 CAS No. 115-20-8
2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 200MG | Get Quote | In Stock |
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| 500MG | 27 | In Stock |
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Biological Information
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Product Name2,2,2-Trichloroethanol
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NoteResearch use only, not for human use.
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Brief Description2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.
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Description2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.(In Vitro):2,2,2-trichloroethanol dilated the middle cerebral artery and activated the potassium channel in cerebrovascular smooth muscle.
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In Vitro2,2,2-trichloroethanol activates a nonclassical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery.
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPotassium Channel
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Recptor5-HT4
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Research Area——
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Indication——
Chemical Information
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CAS Number115-20-8
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Formula Weight149.4
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Molecular FormulaC2H3Cl3O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (669.34 mM)
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SMILESOCC(Cl)(Cl)Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Clark RD, et al. Identification of a 5-HT4 receptor antagonist clinical candidate through side-chain modification. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1697-700.
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