Cart
sales@molnova.com
Oxychlororaphine
CAS No. 550-89-0
Oxychlororaphine( phenazine-1-carboxamide )
Catalog No. M28110 CAS No. 550-89-0
Oxychlororaphine inhibits strongly the growth of Streptomyces sp. 441.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
|
| 2MG | 32 | In Stock |
|
| 5MG | 52 | In Stock |
|
| 10MG | 89 | In Stock |
|
| 25MG | 187 | In Stock |
|
| 50MG | 305 | In Stock |
|
| 100MG | 491 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1107 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameOxychlororaphine
-
NoteResearch use only, not for human use.
-
Brief DescriptionOxychlororaphine inhibits strongly the growth of Streptomyces sp. 441.
-
DescriptionOxychlororaphine inhibits strongly the growth of Streptomyces sp. 441.
-
In VitroOxychloroaphine (1-256 μM; 24 h) has cytotoxicity with IC50 values for A549, HeLa, and SW480 cancer cell lines between 32 and 40 μM.Oxychloroaphine (1-150 μM; A549, HeLa, and SW480 cancer cell lines) causes cell membrane damage, leading to increase apoptosis and leakage of lactate dehydrogenase, and increases production of cytochrome c protein.Oxychloroaphine (32 μM; A549 and SW480 cells) induces cycle arrest at G1 phase and induction of sub-G phase.Oxychloroaphine (48 h; A549 cells) induces downregulation of antiapoptotic Bcl-2 protein and the activation of proapoptotic protein caspase-3 led to the cleavage of PARP. Cell Viability AssayCell Line:A549, HeLa, and SW480 cancer cell lines Concentration:1, 2, 4, 8, 16, 32, 64, 128, and 256 μM Incubation Time:24 hours Result:Inhibited cell proliferative in a dose-dependent manner.
-
In Vivo——
-
Synonymsphenazine-1-carboxamide
-
PathwayGPCR/G Protein
-
TargetAntibacterial
-
RecptorCarboxylesterase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number550-89-0
-
Formula Weight223.235
-
Molecular FormulaC13H9N3O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 10 mg/mL (44.80 mM)
-
SMILESNC(=O)c1cccc2nc3ccccc3nc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Ceforanide
Ceforanide is a second-generation cephalosporin antibiotic with bactericidal activity. Ceforanide causes inhibition of bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall.
-
Magainin 2
Magainin II is a member of the antimicrobial peptides familyMagainin 2 exhibits bactericidal effects and induces morphological changes in Escherichia coli regarding early apoptosis. Magainin 2 induces the expression of a bacterial protein with affinity for the caspase substrate and effects the expression of RecA as a caspase-like protein.
-
RWJ-49815
A potent bactericidal agent that inhibits the KinA autophosphorylation with IC50 of 1.6 uM.
