Lactisole
CAS No. 150436-68-3
Lactisole( 2-(4-Methoxyphenoxy)propanoic acid )
Catalog No. M28055 CAS No. 150436-68-3
Lactisole is an inhibitor of the glucose-sensing receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 31 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 27 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameLactisole
-
NoteResearch use only, not for human use.
-
Brief DescriptionLactisole is an inhibitor of the glucose-sensing receptor.
-
DescriptionLactisole is an inhibitor of the glucose-sensing receptor.(In Vitro):In MIN6 cells, in a dose-dependent manner, lactisole inhibited insulin secretion induced by sweeteners, acesulfame-K, sucralose and glycyrrhizin. The IC50 was ~4 mmol/l. Lactisole attenuated the elevation of cytoplasmic Ca2+ concentration ([Ca2+]c) evoked by sucralose and acesulfame-K but did not affect the elevation of intracellular cAMP concentration ([cAMP]c) induced by these sweeteners. Lactisole also inhibited the action of glucose in MIN6 cells. Thus, lactisole significantly reduced elevations of intracellular [NADH] and intracellular [ATP] induced by glucose, and also inhibited glucose-induced insulin secretion.
-
In Vitro——
-
In Vivo——
-
Synonyms2-(4-Methoxyphenoxy)propanoic acid
-
PathwayOthers
-
TargetOther Targets
-
RecptorApoptosis|PKG
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number150436-68-3
-
Formula Weight218.184
-
Molecular FormulaC10H11NaO4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (572.92 mM)
-
SMILES[Na+].COc1ccc(OC(C)C([O-])=O)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Pyrocatechol
Pyrocatechol its sulfonic acid is often present in the urine of many mammals. Small amounts of catechol occur naturally in fruits and vegetables along with the enzyme polyphenol oxidase. Upon mixing the enzyme with the substrate and exposure to oxygen (as when a potato or apple is cut) the colorless catechol oxidizes to reddish-brown benzoquinone derivatives.
-
α-Galactosylceramide
α-Galactosylceramide is a synthetic glycolipid with antitumorial and immunostimulatory and is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide and CD1d can bind to the T cell antigen receptor of NKT cells.
-
Steppogenin
Steppogenin exhibits significant tyrosinase inhibition activity, ;it also shows strong mushroom tyrosinase inhibitory activity with IC(50) values lower than 50 microM, more potent than kojic acid (IC(50) = 71.6 microM), a well-known tyrosinase inhibitor.
Cart
sales@molnova.com