1H-Pyrazole is a versatile building block with a vast applications in organic synthesis. The derivatives of Pyrazole are used in medicine for their analgesic anti-inflammatory antipyretic antiarrhythmic tranquilizing muscle relaxing psychoanaleptic anticonvulsant monoamineoxidase inhibiting antidiabetic and antibacterial activities.

Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani.

oxepinac is an effective and well-tolerated compound for the treatment of painful osteoarthritis. oxepinac has no teratogenic effect on mouse and rabbit fetuses in animal experiments.