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MSC 2032964A
CAS No. 1124381-43-6
MSC 2032964A( MSC-2032964A | MSC2032964A | MSC 2032964A )
Catalog No. M27999 CAS No. 1124381-43-6
MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 178 | In Stock |
|
| 2MG | 93 | In Stock |
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| 5MG | 152 | In Stock |
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| 10MG | 240 | In Stock |
|
| 25MG | 392 | In Stock |
|
| 50MG | 548 | In Stock |
|
| 100MG | 737 | In Stock |
|
| 200MG | 1014 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMSC 2032964A
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NoteResearch use only, not for human use.
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Brief DescriptionMSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
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DescriptionMSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
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In Vitro——
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In Vivo——
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SynonymsMSC-2032964A | MSC2032964A | MSC 2032964A
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PathwayOthers
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TargetOther Targets
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RecptorCalcium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number1124381-43-6
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Formula Weight362.316
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Molecular FormulaC16H13F3N6O
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Purity>98% (HPLC)
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Solubility——
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SMILESFC(F)(F)c1cc(NC2CC2)n2nc(NC(=O)c3cccnc3)nc2c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Samy MEROUEH, et al. Preparation of pyrazolyl acylpyrazolines for the treatment of pain. WO2020061303A1
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