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Dimethindene
CAS No. 5636-83-9
Dimethindene( Dimetindene | Dimetindeno )
Catalog No. M27978 CAS No. 5636-83-9
Dimethylbutyl is an antihistamine/anticholinergic drug. It is administered orally and used to relieve itching locally.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 107 | In Stock |
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| 10MG | 158 | In Stock |
|
| 25MG | 236 | In Stock |
|
| 50MG | 343 | In Stock |
|
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDimethindene
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NoteResearch use only, not for human use.
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Brief DescriptionDimethylbutyl is an antihistamine/anticholinergic drug. It is administered orally and used to relieve itching locally.
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DescriptionDimethylbutyl is an antihistamine/anticholinergic drug. It is administered orally and used to relieve itching locally.(In Vitro):In follicle-enclosed Xenopus oocytes, Dimethindene (5-500 μM) decreases Cromakalim cromakalim-induced K+ currents (IC50 = 29.5 μM).(In Vivo):In C57BL/6 mice with skin wound healing, Dimethindene (0.25 mg; i.p.) impairs cutaneous wound healing and delays skin wound closure.
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In VitroDimethindene (5-500 μM; follicle-enclosed Xenopus oocytes) decreases Cromakalim cromakalim-induced K+ currents with an IC50 value of 29.5 μM.
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In VivoDimethindene (0.25 mg; i.p.; once; C57BL/6 mice with skin WH) impaires cutaneous wound healing (WH) and delays skin wound closure. Animal Model:C57BL/6 mice with skin WH Dosage:0.25 mg Administration: intraperitoneal injection; once Result:Delayed skin wound closure as compared to vehicle treated mice.
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SynonymsDimetindene | Dimetindeno
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PathwayOthers
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TargetOther Targets
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RecptorHedgehog|Apoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number5636-83-9
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Formula Weight292.426
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Molecular FormulaC20H24N2
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Officioso A, et al. Triggering of Erythrocyte Death by Triparanol. Toxins (Basel). 2015 Aug 24;7(8):3359-71.
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