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Diloxanide
CAS No. 579-38-4
Diloxanide( RD 3803 | RD-3803 | RD3803 | Diloxanide | Diloxanid | Diloxanida )
Catalog No. M27976 CAS No. 579-38-4
Diloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 25MG | 34 | In Stock |
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| 50MG | 47 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDiloxanide
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NoteResearch use only, not for human use.
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Brief DescriptionDiloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.
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DescriptionDiloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.
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In Vitro——
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In VivoDiloxanide is hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate.Diloxanide furoate (oral administraion; 75-200 mg/kg; 3 days; once daily) is effective at different dose of dayin weanling rats. At 200 mg/kg, 100% of the treated rats are cured and no amoebic lesions are observed in the caecum. Besides, 85%,77%, and 44.4% of the treated rats are cured at the dose 150 mg/kg, 100 mg/kg, and 75 mg/kg, respectively. The ED50 value is 77.9 mg/kg for this agent in rats.
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SynonymsRD 3803 | RD-3803 | RD3803 | Diloxanide | Diloxanid | Diloxanida
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PathwayMicrobiology/Virology
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TargetParasite
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RecptorTNNI3 Interacting Kinase (TNNI3K)
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Research Area——
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Indication——
Chemical Information
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CAS Number579-38-4
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Formula Weight234.08
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Molecular FormulaC9H9Cl2NO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (142.39 mM)
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SMILESCN(C(=O)C(Cl)Cl)c1ccc(O)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Patterson JR, et, al. Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf. J Med Chem. 2021 Nov 11;64(21):15651-15670.
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