Diloxanide

Research use only, not for human use.

Diloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.

Diloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.

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Diloxanide is hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate.Diloxanide furoate (oral administraion; 75-200 mg/kg; 3 days; once daily) is effective at different dose of dayin weanling rats. At 200 mg/kg, 100% of the treated rats are cured and no amoebic lesions are observed in the caecum. Besides, 85%,77%, and 44.4% of the treated rats are cured at the dose 150 mg/kg, 100 mg/kg, and 75 mg/kg, respectively. The ED50 value is 77.9 mg/kg for this agent in rats.

RD 3803 | RD-3803 | RD3803 | Diloxanide | Diloxanid | Diloxanida

Microbiology/Virology

Parasite

TNNI3 Interacting Kinase (TNNI3K)

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579-38-4

234.08

C9H9Cl2NO2

>98% (HPLC)

In Vitro:?DMSO : 33.33 mg/mL (142.39 mM)

CN(C(=O)C(Cl)Cl)c1ccc(O)cc1

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(-20℃)

With Ice Pack

≥ 2 years