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Cerlapirdine

CAS No. 925448-93-7

Cerlapirdine( SAM531 | SAM-531 | SAM 531 | PF-05212365 | P -05212365 | WAY-262,531 )

Catalog No. M27966 CAS No. 925448-93-7

Cerlapirdine is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzheimer's disease and schizophrenia. It works by acting as a selective 5-HT6 receptor antagonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 199 In Stock
5MG 169 In Stock
10MG 275 In Stock
25MG 543 In Stock
50MG 764 In Stock
100MG 1051 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Cerlapirdine
  • Note
    Research use only, not for human use.
  • Brief Description
    Cerlapirdine is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzheimer's disease and schizophrenia. It works by acting as a selective 5-HT6 receptor antagonist.
  • Description
    Cerlapirdine is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzheimer's disease and schizophrenia. It works by acting as a selective 5-HT6 receptor antagonist.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SAM531 | SAM-531 | SAM 531 | PF-05212365 | P -05212365 | WAY-262,531
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    hSmo|mSmo
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    925448-93-7
  • Formula Weight
    409.5
  • Molecular Formula
    C22H23N3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 41.67 mg/mL (101.76 mM)
  • SMILES
    CN(C)CCCOc1ccc2n[nH]c(c2c1)S(=O)(=O)c1cccc2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lauressergues E, et al. Pharmacological evaluation of a series of smoothened antagonists in signaling pathways and after topical application in a depilated mouse model. Pharmacol Res Perspect. 2016 Mar 4;4(2):e00214.
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