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VPC-13566

CAS No. 218464-59-6

VPC-13566( VPC13566 | VPC 13566 )

Catalog No. M27935 CAS No. 218464-59-6

VPC-13566 is a BF3-specific small molecule, which effectively inhibited the androgen receptor transcriptional activity and displaced the BAG1L peptide from the BF3 pocket.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	191	Get Quote
10MG	267	Get Quote
25MG	466	Get Quote
50MG	674	Get Quote
100MG	954	Get Quote
500MG	1881	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

VPC-13566
Note

Research use only, not for human use.
Brief Description

VPC-13566 is a BF3-specific small molecule, which effectively inhibited the androgen receptor transcriptional activity and displaced the BAG1L peptide from the BF3 pocket.
Description

VPC-13566 is a BF3-specific small molecule, which effectively inhibited the androgen receptor transcriptional activity and displaced the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines and reduces the growth of AR-dependent prostate cancer xenograft tumors in mice.
In Vitro

——
In Vivo

——
Synonyms

VPC13566 | VPC 13566
Pathway

Endocrinology/Hormones
Target

Androgen Receptor (AR)
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

218464-59-6
Formula Weight

258.324
Molecular Formula

C18H14N2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (387.12 mM)
SMILES

Cc1cccc2c(c[nH]c12)-c1ccc2ccccc2n1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Anthony Boitano, et al. Aryl hydrocarbon receptor antagonists and methods of use thereof for treating various diseases. WO2020051207A2

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