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TG6-129
CAS No. 1164464-14-5
TG6-129( TG6 129 | TG6129 )
Catalog No. M27930 CAS No. 1164464-14-5
TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 339 | In Stock |
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| 5MG | 240 | In Stock |
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| 10MG | 427 | In Stock |
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| 25MG | 702 | In Stock |
|
| 50MG | 918 | In Stock |
|
| 100MG | 1293 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2623 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTG6-129
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NoteResearch use only, not for human use.
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Brief DescriptionTG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 μM.
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DescriptionTG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 μM. TG6-129 reduces the expression of COX-2, IL-1β, IL-6, IL-12, IL-23 and TNF-α induced by the EP2-selective agonist butaprost in P388D1 macrophages.
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In Vitro——
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In Vivo——
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SynonymsTG6 129 | TG6129
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PathwayGPCR/G Protein
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TargetProstaglandin Receptor
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Recptorestrogen receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1164464-14-5
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Formula Weight491.57
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Molecular FormulaC20H18FN5O3S3
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Purity>98% (HPLC)
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Solubility——
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SMILESCCc1nnc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)\C=C\c3ccc(F)cc3)cc2)s1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Guo S, et al. GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models. Breast Cancer Res Treat. 2020;180(2):359-368.
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