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INI-43
CAS No. 881046-01-1
INI-43( INI 43 | INI43 | INI-43 )
Catalog No. M27884 CAS No. 881046-01-1
INI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpnβ1 cargoes, NFAT, NFκB, AP-1 and NF.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 93 | In Stock |
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| 5MG | 85 | In Stock |
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| 10MG | 136 | In Stock |
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| 25MG | 275 | In Stock |
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| 50MG | 423 | In Stock |
|
| 100MG | 625 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameINI-43
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NoteResearch use only, not for human use.
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Brief DescriptionINI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpnβ1 cargoes, NFAT, NFκB, AP-1 and NF.
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DescriptionINI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpnβ1 cargoes, NFAT, NFκB, AP-1 and NF.
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In Vitro——
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In Vivo——
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SynonymsINI 43 | INI43 | INI-43
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PathwayOthers
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TargetOther Targets
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RecptorPLD1|PLD2|Dopamine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number881046-01-1
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Formula Weight385.475
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Molecular FormulaC22H23N7
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 10 mg/mL (25.94 mM)
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SMILESCN(C)CCCn1c(N)c(-c2nc3ccccc3[nH]2)c2nc3ccccc3nc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Skafi N, et al. Phospholipase D: A new mediator during high phosphate-induced vascular calcification associated with chronic kidney disease. J Cell Physiol. 2019 Apr;234(4):4825-4839.
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