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Dehydroepiandrosterone sulfate

CAS No. 651-48-9

Dehydroepiandrosterone sulfate( Prasterone sulfate | PB-005 | PB005 | PB 005 | DHEA sulfate | DHEAS | )

Catalog No. M27837 CAS No. 651-48-9

Prasterone sulfate is a HSD11B1 expression inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 78 In Stock
5MG 70 In Stock
10MG 114 In Stock
25MG 244 In Stock
50MG 378 In Stock
100MG 547 In Stock
200MG 795 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Dehydroepiandrosterone sulfate
  • Note
    Research use only, not for human use.
  • Brief Description
    Prasterone sulfate is a HSD11B1 expression inhibitor.
  • Description
    Prasterone sulfate is a HSD11B1 expression inhibitor.(In Vitro):Dehydroepiandrosterone sulfate selectively increases the length of neurites containing the dendritic marker MAP-2 and increases neuronal excitability when directly applied to septal-preoptic neurons.(In Vivo):Chronic administration of Dehydroepiandrosterone sulfate produces a dose-dependent effect on performance. In male Sprague-Dawley rats, Dehydroepiandrosterone sulfate (5-20 mg/kg; s.c.) is significantly effective in improving latency to reach the platform.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Sixty-four male Sprague-Dawley rats, approximately 90 days of age (300-400 g).Dosage:5, 10, or 20 mg/kg.Administration:Subcutaneous injection starting 7 days post-surgery and 1 h prior to all behavioral testing.Result:Significantly effective in improving latency to reach the platform as compared to injured rats receiving vehicle.
  • Synonyms
    Prasterone sulfate | PB-005 | PB005 | PB 005 | DHEA sulfate | DHEAS |
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    FLT3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    651-48-9
  • Formula Weight
    368.49
  • Molecular Formula
    C19H28O5S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (271.38 mM)
  • SMILES
    [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OS(O)(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.A Eriksson, et al. The Novel Tyrosine Kinase Inhibitor AKN-028 Has Significant Antileukemic Activity in Cell Lines and Primary Cultures of Acute Myeloid Leukemia. Blood Cancer J. 2012 Aug 3;2(8):e81.
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