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TT01001
CAS No. 1022367-69-6
TT01001( TT-01001 | TT 01001 | Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate )
Catalog No. M27799 CAS No. 1022367-69-6
TT01001 is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 can be used in studies about the treatment of type II diabetes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 93 | In Stock |
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| 10MG | 155 | In Stock |
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| 25MG | 312 | In Stock |
|
| 50MG | 492 | In Stock |
|
| 100MG | 700 | In Stock |
|
| 200MG | 918 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTT01001
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NoteResearch use only, not for human use.
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Brief DescriptionTT01001 is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 can be used in studies about the treatment of type II diabetes.
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DescriptionTT01001 is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 can be used in studies about the treatment of type II diabetes.(In Vivo):In type II diabetes model db/db mice, TT01001 improved hyperglycemia, hyperlipidemia, and glucose intolerance, and its efficacy was equivalent to that of pioglitazone, without the pioglitazone-associated weight gain. Mitochondrial complex II + III activity of the skeletal muscle was significantly increased in db/db mice. TT01001 significantly suppressed the elevated activity of the complex II + III.
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In Vitro——
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In Vivo——
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SynonymsTT-01001 | TT 01001 | Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate
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PathwayOthers
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TargetOther Targets
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RecptorRIP2
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Research Area——
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Indication——
Chemical Information
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CAS Number1022367-69-6
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Formula Weight376.3
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Molecular FormulaC15H19Cl2N3O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESCCOC(=O)N1CCC(CC1)NC(=S)Nc1cc(Cl)cc(Cl)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Sari 59-801
Sari 59-801 is a novel, orally effective hypoglycemic compound that appears to act largely by stimulation of insulin release. SARI-59-801 was more potent in producing hypoglycemia (ED25 = 47 mg/kg) than their lean littermates (ED25 = 131 mg/kg).
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Divalproex Sodium
Divalproex Sodium binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings.
