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TT01001
CAS No. 1022367-69-6
TT01001( TT-01001 | TT 01001 | Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate )
Catalog No. M27799 CAS No. 1022367-69-6
TT01001 is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 can be used in studies about the treatment of type II diabetes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 93 | In Stock |
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| 10MG | 155 | In Stock |
|
| 25MG | 312 | In Stock |
|
| 50MG | 492 | In Stock |
|
| 100MG | 700 | In Stock |
|
| 200MG | 918 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTT01001
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NoteResearch use only, not for human use.
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Brief DescriptionTT01001 is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 can be used in studies about the treatment of type II diabetes.
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DescriptionTT01001 is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 can be used in studies about the treatment of type II diabetes.(In Vivo):In type II diabetes model db/db mice, TT01001 improved hyperglycemia, hyperlipidemia, and glucose intolerance, and its efficacy was equivalent to that of pioglitazone, without the pioglitazone-associated weight gain. Mitochondrial complex II + III activity of the skeletal muscle was significantly increased in db/db mice. TT01001 significantly suppressed the elevated activity of the complex II + III.
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In Vitro——
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In Vivo——
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SynonymsTT-01001 | TT 01001 | Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate
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PathwayOthers
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TargetOther Targets
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RecptorRIP2
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Research Area——
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Indication——
Chemical Information
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CAS Number1022367-69-6
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Formula Weight376.3
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Molecular FormulaC15H19Cl2N3O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESCCOC(=O)N1CCC(CC1)NC(=S)Nc1cc(Cl)cc(Cl)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Haile PA, et al. Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases. J Med Chem. 2019 Jul 25;62(14):6482-6494.
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