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TCS 46b

CAS No. 302799-86-6

TCS 46b( —— )

Catalog No. M27726 CAS No. 302799-86-6

TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    TCS 46b
  • Note
    Research use only, not for human use.
  • Brief Description
    TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.
  • Description
    TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Sprague?Dawley rats, 6-hydroxydopamine-lesioned (6-OHDA) rat modelDosage:10 and 30 mg/kg Administration:PO or IP, once Result:Showed significant potentiation of the effects of L-DOPA in this model.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    NMDAR
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    302799-86-6
  • Formula Weight
    345.446
  • Molecular Formula
    C22H23N3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (289.49 mM)
  • SMILES
    O=c1[nH]c2ccc(cc2[nH]1)C#CCN1CCC(Cc2ccccc2)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fdez Galván I, et al. Solvent Effects on the Structure and Spectroscopy of the Emitting States of 1-Phenylpyrrole. J Chem Theory Comput. 2011 Jun 14;7(6):1850-7.
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