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MK-4827 Racemate

CAS No. 1038915-75-1

MK-4827 Racemate( Niraparib Racemate | 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide )

Catalog No. M27657 CAS No. 1038915-75-1

MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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10MG	140	Get Quote
25MG	267	Get Quote
50MG	466	Get Quote
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Biological Information

Product Name

MK-4827 Racemate
Note

Research use only, not for human use.
Brief Description

MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
Description

MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
In Vitro

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In Vivo

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Synonyms

Niraparib Racemate | 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide
Pathway

Cell Cycle/DNA Damage
Target

PARP
Recptor

DNA/RNA Synthesis
Research Area

——
Indication

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Chemical Information

CAS Number

1038915-75-1
Formula Weight

320.396
Molecular Formula

C19H20N4O
Purity

>98% (HPLC)
Solubility

——
SMILES

NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)C1CCCNC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26(41):8857-8861.

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