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FR 122047 hydrochloride

CAS No. 130717-51-0

FR 122047 hydrochloride( 1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride | 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride )

Catalog No. M27630 CAS No. 130717-51-0

FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
5MG	100	In Stock
10MG	167	In Stock
25MG	341	In Stock
50MG	538	In Stock
100MG	768	In Stock
200MG	1014	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

FR 122047 hydrochloride
Note

Research use only, not for human use.
Brief Description

FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.
Description

FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.
In Vitro

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In Vivo

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Synonyms

1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride | 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride
Pathway

Chromatin/Epigenetic
Target

COX
Recptor

Antifection|HIV|Apoptosis|PI3K
Research Area

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Indication

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Chemical Information

CAS Number

130717-51-0
Formula Weight

459.99
Molecular Formula

C23H25N3O3S·HCl
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (217.40 mM)
SMILES

O=C(C1=NC(C(C=C2)=CC=C2OC)=C(C(C=C3)=CC=C3OC)S1)N4CCN(C)CC4.Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Hu K, et al. Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. Planta Med. 2000 Aug;66(6):564-7.

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