8-Hydroxy-DPAT hydrobromide

CAS No. 76135-31-4

8-Hydroxy-DPAT hydrobromide( 8-OH-DPAT hydrobromide )

Catalog No. M27597 CAS No. 76135-31-4

8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has a selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 37 In Stock
10MG 61 In Stock
25MG 132 In Stock
50MG 237 In Stock
100MG 423 In Stock
200MG Get Quote In Stock
500MG 918 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    8-Hydroxy-DPAT hydrobromide
  • Note
    Research use only, not for human use.
  • Brief Description
    8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has a selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.
  • Description
    8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has a selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    8-OH-DPAT hydrobromide
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    PARP1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    76135-31-4
  • Formula Weight
    328.29
  • Molecular Formula
    C16H25NO·HBr
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (76.15 mM)
  • SMILES
    OC1=C2C[C@H](CCC2=CC=C1)N(CCC)CCC.Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Almahli H, Hadchity E, Jaballah MY, Daher R, Ghabbour HA, Kabil MM, Al-Shakliah NS, Eldehna WM. Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer. Bioorg Chem. 2018 Apr;77:443-456.
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