Tylvalosin tartrate
CAS No. 63428-13-7
Tylvalosin tartrate( Acetylisovaleryltylosin Tartrate )
Catalog No. M27525 CAS No. 63428-13-7
Tylvalosin tartrate is a macrolide antibiotic that can against Gram-positive bacteria.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 40 | In Stock |
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| 25MG | 29 | In Stock |
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| 50MG | 35 | In Stock |
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| 100MG | 49 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 86 | In Stock |
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| 1G | 126 | In Stock |
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Biological Information
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Product NameTylvalosin tartrate
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NoteResearch use only, not for human use.
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Brief DescriptionTylvalosin tartrate is a macrolide antibiotic that can against Gram-positive bacteria.
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DescriptionTylvalosin tartrate is a macrolide antibiotic that can against Gram-positive bacteria.
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In VitroApoptosis Analysis Cell Line:Porcine neutrophils Concentration:0.1, 1.0, or 10 μg/mL Incubation Time:0.5, 1 h Result:Resulted induction of concentration- and time-dependent apoptosis in porcine monocyte-derived macrophages.
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In VivoAnimal Model:PRRSV-free commercial breed piglets Dosage:800 mg/kg Aivlosin (20% Tylvalosin Tartrate Premix)Administration: po; 7-14 days Result:Attenuated the increase in total white blood cells induced by immunization at day one post-immunization (DPI) and induced an increase in monocyte counts after seven DPI.Attenuate the reduction in the percentage of CD8+ T cells induced by PRRSV-inactivated vaccine immunization at seven DPI.
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SynonymsAcetylisovaleryltylosin Tartrate
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorBRD4 (1)
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Research Area——
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Indication——
Chemical Information
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CAS Number63428-13-7
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Formula Weight1192.34
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Molecular FormulaC57H93NO25
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (83.87 mM)
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SMILESO[C@@H](C(O)=O)[C@H](C(O)=O)O.CC[C@H]1OC(C[C@H]([C@@H]([C@H]([C@H](C[C@H](C(/C=C\C(C)=C/[C@@H]1CO[C@@H]2O[C@@H]([C@H]([C@H]([C@H]2OC)OC)O)C)=O)C)CC=O)O[C@@H]3O[C@@H]([C@H]([C@H](N(C)C)[C@H]3O)O[C@@H]4C[C@H]([C@@H]([C@](O)(O4)C)OC(CC(C)C)=O)C)C)C)OC(C)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhang M, et al. Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC). J Med Chem. 2018 Apr 12;61(7):3037-3058.
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