Tylvalosin tartrate

CAS No. 63428-13-7

Tylvalosin tartrate( Acetylisovaleryltylosin Tartrate )

Catalog No. M27525 CAS No. 63428-13-7

Tylvalosin tartrate is a macrolide antibiotic that can against Gram-positive bacteria.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 40 In Stock
25MG 29 In Stock
50MG 35 In Stock
100MG 49 In Stock
200MG Get Quote In Stock
500MG 86 In Stock
1G 126 In Stock

Biological Information

  • Product Name
    Tylvalosin tartrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Tylvalosin tartrate is a macrolide antibiotic that can against Gram-positive bacteria.
  • Description
    Tylvalosin tartrate is a macrolide antibiotic that can against Gram-positive bacteria.
  • In Vitro
    Apoptosis Analysis Cell Line:Porcine neutrophils Concentration:0.1, 1.0, or 10 μg/mL Incubation Time:0.5, 1 h Result:Resulted induction of concentration- and time-dependent apoptosis in porcine monocyte-derived macrophages.
  • In Vivo
    Animal Model:PRRSV-free commercial breed piglets Dosage:800 mg/kg Aivlosin (20% Tylvalosin Tartrate Premix)Administration: po; 7-14 days Result:Attenuated the increase in total white blood cells induced by immunization at day one post-immunization (DPI) and induced an increase in monocyte counts after seven DPI.Attenuate the reduction in the percentage of CD8+ T cells induced by PRRSV-inactivated vaccine immunization at seven DPI.
  • Synonyms
    Acetylisovaleryltylosin Tartrate
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    BRD4 (1)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    63428-13-7
  • Formula Weight
    1192.34
  • Molecular Formula
    C57H93NO25
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (83.87 mM)
  • SMILES
    O[C@@H](C(O)=O)[C@H](C(O)=O)O.CC[C@H]1OC(C[C@H]([C@@H]([C@H]([C@H](C[C@H](C(/C=C\C(C)=C/[C@@H]1CO[C@@H]2O[C@@H]([C@H]([C@H]([C@H]2OC)OC)O)C)=O)C)CC=O)O[C@@H]3O[C@@H]([C@H]([C@H](N(C)C)[C@H]3O)O[C@@H]4C[C@H]([C@@H]([C@](O)(O4)C)OC(CC(C)C)=O)C)C)C)OC(C)=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang M, et al. Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC). J Med Chem. 2018 Apr 12;61(7):3037-3058.
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