Ivermectin B1a( —— )

Catalog No. M27454 CAS No. 71827-03-7

Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	226	Get Quote
5MG	117	Get Quote
10MG	187	Get Quote
25MG	376	Get Quote
50MG	538	Get Quote
100MG	Get Quote	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Ivermectin B1a
Note

Research use only, not for human use.
Brief Description

Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.
Description

Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.(In Vitro):Ivermectin B1a(0.3 μg/ml) is inactive, whereas in the case of the minor component, ivermectin B1b(0.3 μg/ml) produces 100% mortality of snails.
In Vitro

Ivermectin belongs to the macrocyclic lactone class of avermectins and consists of a mixture of two homologous compounds, ivermectin B1a (not less than 80%) and ivermectin B1b (not more than 20%). Ivermectin B1a, the major component of Ivermectin, is inactive at a concentration of 0.3 μg/ml, whereas in the case of the minor component, ivermectin B1b, the same concentration produces 100% mortality of snails.
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

σ1
Research Area

——
Indication

——

Chemical Information

CAS Number

71827-03-7
Formula Weight

875.09
Molecular Formula

C48H74O14
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (114.27 mM)
SMILES

CC[C@@H]([C@@H]1[C@@H](C)CC[C@]2(C[C@@H]3C[C@@H](C/C=C(C)/[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C6CO[C@H]7[C@]\6(O)[C@H](C(O3)=O)C=C(C)[C@H]7O)O2)O1)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Lan Y, et al. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain. J Med Chem. 2014 Dec 26;57(24):10404-23.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks