Isoflupredone Acetate

Research use only, not for human use.

Isoflupredone Acetate is a corticosteroid with the activity of topical anti-inflammatory.

Isoflupredone Acetate is a corticosteroid with the activity of topical anti-inflammatory.

Isoflupredone acetate (10-4, 10-7, or 10-10 M; 48 or 96 h) mitigates the inflammatory and catabolic effects of IL-1β in synovial and osteochondral explants (from equine cadavers) to a greater extent in low concentrations (10-7 M and 10-10 M) than the high concentration (10-4 M).

Isoflupredone acetate (0.05 mg/kg; i.m.; on days 2 and 4 after the challenge) prevents dry-matter intake and average daily gain reductions, and leads to faster Mannheimia haemolytica-infected clinical improvement when co-treated with Oxytetracycline (HY-B0275). Animal Model:96 weanling heifers (Bronchopneumonia was induced by intrabronchial infusion of Mannheimia haemolytica)Dosage:0.05 mg/kg Administration:i.m.; on days 2 and 4 after the challenge Result:Infection caused a reduction in dry-matter intake and average daily gain (ADG) in heifers.Prevented these reductions and resulted in faster clinical improvement when co-treated with Oxytetracycline (HY-B0275).

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Others

Other Targets

serotonin

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338-98-7

420.477

C23H29FO6

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (297.29 mM)

CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C

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(-20℃)

With Ice Pack

≥ 2 years