2-Fluoroadenine

Research use only, not for human use.

2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.

2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.(In Vitro):In Balb-3T3 cells, 2-Fluoroadenine (0.22, 2.2 and 22 μM; 30 hours) inhibits protein, RNA, and DNA syntheses. In CEM cells, 2-Fluoroadenine (2 μM; 4 hours) inhibits CEM cell growth by targeting one or more enzymes involved in either RNA or protein synthesis. In nonproliferating MRC-5 cells, 2-Fluoroadenine (0-1000 μM; 96 hours) exhibits cytotoxicity.

2-Fluoroadenine (2 μM; 4 hours) inhibits CEM cell growth by targeting one or more enzymes involved in either RNA or protein synthesis.2-Fluoroadenine (0-1000 μM; 96 hours) exhibits cytotoxicity in nonproliferating MRC-5 cells.2-Fluoroadenine (0.22, 2.2 and 22 μM; 30 hours) inhibits protein, RNA, and DNA syntheses in Balb-3T3 cells incubated in serum-free medium. Cell Proliferation Assay Cell Line:CEM cells Concentration:2 μM Incubation Time:4 hours Result:Inhibited CEM cell growth by targeting one or more enzymes involved in either RNA or protein synthesis.Cell Cytotoxicity Assay Cell Line:MRC-5 cells Concentration:0-1000 μM Incubation Time:4 hours Result:Exhibited cytotoxicity in nonproliferating MRC-5 cells.

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NSC 27364 | 2- Fluoro-6-Aminopurine

Cell Cycle/DNA Damage

DNA/RNA Synthesis

SARS-CoV

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700-49-2

153.12

C5H4FN5

>98% (HPLC)

In Vitro:?DMSO : 20.83 mg/mL (136.04 mM)

Nc1[nH]c(F)nc2ncnc12

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(-20℃)

With Ice Pack

≥ 2 years