Acriflavine Hydrochloride
CAS No. 8063-24-9
Acriflavine Hydrochloride( Acriflavine HCl )
Catalog No. M27171 CAS No. 8063-24-9
Acriflavine Hydrochloride is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 43 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 38 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAcriflavine Hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionAcriflavine Hydrochloride is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.
-
DescriptionAcriflavine Hydrochloride is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.
-
In Vitro——
-
In Vivo——
-
SynonymsAcriflavine HCl
-
PathwayAngiogenesis
-
TargetHIF/HIF Prolyl-hydroxylase
-
RecptorAntifungal
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number8063-24-9
-
Formula Weight259.74
-
Molecular FormulaC14H14ClN3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES[Cl-].C[n+]1c2cc(N)ccc2cc2ccc(N)cc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Gurram RK, et al. Caerulomycin A enhances transforming growth factor-β (TGF-β)-Smad3 protein signaling by suppressing interferon-γ (IFN-γ)-signal transducer and activator of transcription 1 (STAT1) protein signaling to expand regulatory T cells (Tregs). J Biol Chem. 2014 Jun 20;289(25):17515-28.
molnova catalog
related products
-
103D5R
103D5R is a small-molecule inhibitor of HIF-1α that displays an EC50 of 35 uM against hypoxia-induced alkaline phosphatase enzymatic reporter activity.
-
GN44028
GN44028 is a hypoxia-inducible factor inhibitor of (HIF)-1 (IC50: 14 nM). GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity.
-
Molidustat
Molidustat (BAY 85-3934) is an orally active small molecule inhibitor of hypoxia inducible factor prolyl hydroxylase (HIF-PH) with IC50 of 480 nM, 280 nM and 450 nM for PHD1, PHD2, and PHD3, respectively.
Cart
sales@molnova.com