Acriflavine Hydrochloride( Acriflavine HCl )

Catalog No. M27171 CAS No. 8063-24-9

Acriflavine Hydrochloride is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Acriflavine Hydrochloride
Note

Research use only, not for human use.
Brief Description

Acriflavine Hydrochloride is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.
Description

Acriflavine Hydrochloride is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.
In Vitro

——
In Vivo

——
Synonyms

Acriflavine HCl
Pathway

Angiogenesis
Target

HIF/HIF Prolyl-hydroxylase
Recptor

Antifungal
Research Area

——
Indication

——

Chemical Information

CAS Number

8063-24-9
Formula Weight

259.74
Molecular Formula

C14H14ClN3
Purity

>98% (HPLC)
Solubility

——
SMILES

[Cl-].C[n+]1c2cc(N)ccc2cc2ccc(N)cc12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Gurram RK, et al. Caerulomycin A enhances transforming growth factor-β (TGF-β)-Smad3 protein signaling by suppressing interferon-γ (IFN-γ)-signal transducer and activator of transcription 1 (STAT1) protein signaling to expand regulatory T cells (Tregs). J Biol Chem. 2014 Jun 20;289(25):17515-28.

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