Cart
sales@molnova.com
Home - Products - Angiogenesis - PDE - Ro 20-1724

Ro 20-1724

CAS No. 29925-17-5

Ro 20-1724( Ro20-1724 | Ro 20-1724 | Ro-20-1724 | 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone )

Catalog No. M27133 CAS No. 29925-17-5

Ro20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 29 In Stock
5MG 38 In Stock
10MG 61 In Stock
25MG 122 In Stock
50MG 174 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Ro 20-1724
  • Note
    Research use only, not for human use.
  • Brief Description
    Ro20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.
  • Description
    Ro20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.(In Vivo):RO-20-1724 was found to not only improve learning and memory in MWM and PA paradigms but also restore STZ induced elevation in cholinesterase activity. Further, RO-20-1724 significantly reduced malondialdehyde and nitrite levels, and restored the glutathione levels indicating attenuation of oxidative stress.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Ro20-1724 | Ro 20-1724 | Ro-20-1724 | 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    IL-8| NOD2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    29925-17-5
  • Formula Weight
    278.352
  • Molecular Formula
    C15H22N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 50 mg/mL (179.63 mM)
  • SMILES
    CCCCOc1cc(CC2CNC(=O)N2)ccc1OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Rickard DJ, et al. Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway. PLoS One. 2013;8(8):e69619. Published 2013 Aug 1.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • PF-00489791

    PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.

  • Carbazeran

    Carbazeran is an inhibitor of PDE2 and PDE3 and can be used for studies about metabolic diseases. Carbazeran shows inotropic and chronotropic effects in vivo(EC50 = 100 μM).

  • PDE IV-IN-1

    PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary disease and other inflammatory diseases, and is a potential compound for the study of depression.

Sign In Join Free