Tiomolibdate diammonium( Ammonium molybdenum sulfide | Ammonium tetrathiomolybdate | ATTM | Coprexa | NSC 286644 )

Catalog No. M27125 CAS No. 15060-55-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Tiomolibdate diammonium
Note

Research use only, not for human use.
Brief Description

Tiomolibdate diammonium is an inhibitor of superoxide dismutase 1 (SOD1) exerting antiangiogenic and antitumor activities.
Description

Tiomolibdate diammonium is an inhibitor of superoxide dismutase 1 (SOD1) exerting antiangiogenic and antitumor activities. Tiomolibdate diammonium inhibits the activities of cuproenzymes, including SOD1 and COX.
In Vitro

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In Vivo

Ammonium tetrathiomolybdate(VI) (ATTM) (i.v.; 10?mg/kg) confers significant neuroprotection. Animal Model:Wistar Rats Dosage:10?mg/kg Administration:Intravenous Result:Showed improved functional activity at both 24 h and 7-days post-reperfusion, in parallel with a significant reduction in infarct size.
Synonyms

Ammonium molybdenum sulfide | Ammonium tetrathiomolybdate | ATTM | Coprexa | NSC 286644
Pathway

Others
Target

Other Targets
Recptor

Apoptosis| ERK1| ERK2
Research Area

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Indication

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1.Hanna Piotrowska, et al. DMU-212 inhibits tumor growth in xenograft model of human ovarian cancer. Biomed Pharmacother. 2014 May;68(4):397-400.

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