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Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride
CAS No. 2245697-85-0
Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride( —— )
Catalog No. M27022 CAS No. 2245697-85-0
Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 38 | Get Quote |
|
| 10MG | 59 | Get Quote |
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| 25MG | 105 | Get Quote |
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| 50MG | 177 | Get Quote |
|
| 100MG | 336 | Get Quote |
|
| 200MG | 509 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameThalidomide-O-amido-PEG4-C2-NH2 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionThalidomide-O-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.
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DescriptionThalidomide-O-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2245697-85-0
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Formula Weight587.02
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Molecular FormulaC25H35ClN4O10
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (85.18 mM)
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SMILESCl.NCCOCCOCCOCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kinoshita M, et al. A rapid and facile preparation of APTS-labeled N-glycans by combination of ion pair-assisted extraction and HILIC-SPE for routine glycan analysis. J Pharm Biomed Anal. 2021 Feb 20;195:113875.
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