Cart
sales@molnova.com
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
CAS No. 2204226-02-6
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride( —— )
Catalog No. M27020 CAS No. 2204226-02-6
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 36 | In Stock |
|
| 5MG | 29 | In Stock |
|
| 10MG | 42 | In Stock |
|
| 25MG | 69 | In Stock |
|
| 50MG | 100 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameThalidomide-O-amido-PEG-C2-NH2 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionThalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.
-
DescriptionThalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorMitochondrial Metabolism
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2204226-02-6
-
Formula Weight454.86
-
Molecular FormulaC19H23ClN4O7
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (274.81 mM)
-
SMILESCl.NCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Wang Y, et al. A new point mutation in the iron-sulfur subunit of succinate dehydrogenase confers resistance to boscalid in Sclerotinia sclerotiorum. Mol Plant Pathol. 2015 Sep;16(7):653-61.
molnova catalog
related products
-
1-39-Corticotropin (...
Adrenocorticotropic Hormone (ACTH) (1-39) human(TFA),a member of the melanocortin family, is a melanocortin receptor agonist. It stimulates production of CS by the adrenals, but melanocortin receptors are also found in the central nervous system (CNS) and on immune cells.
-
Ondansetron
Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
-
7,4-Dihydroxyhomoiso...
(3R)-7,4’-Dihydrohomoisoflavanone, a natural compound, exhibits potent antibacterial properties against both S. aureus and methicillin-resistant Staphylococcus aureus (MRSA).
