Propargyl-PEG11-methane( —— )

Catalog No. M27004 CAS No. 2250411-18-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Propargyl-PEG11-methane
Note

Research use only, not for human use.
Brief Description

Propargyl-PEG11-methane is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
Description

Propargyl-PEG11-methane is a PEG-based PROTAC linker that can be used to synthesize PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Ras-related GTPases
Research Area

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Indication

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1. Yan C, et al. Discovery and characterization of small molecules that target the GTPase Ral. Nature. 2014;515(7527):443-447.

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