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Mc-Val-Cit-PAB-Cl
CAS No. 1639351-92-0
Mc-Val-Cit-PAB-Cl( —— )
Catalog No. M26985 CAS No. 1639351-92-0
Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 233 | In Stock |
|
| 10MG | 375 | In Stock |
|
| 25MG | 706 | In Stock |
|
| 50MG | 918 | In Stock |
|
| 100MG | 1274 | In Stock |
|
| 200MG | 1721 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMc-Val-Cit-PAB-Cl
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NoteResearch use only, not for human use.
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Brief DescriptionMc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE.
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DescriptionMc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). Mc-Val-Cit-PAB-Cl is a cleavable ADC linker.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1639351-92-0
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Formula Weight591.11
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Molecular FormulaC28H39ClN6O6
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)[C@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CCl)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Remirez D, et al. Mechanism of protection of lobenzarit against paracetamol-induced toxicity in rat hepatocytes. Eur J Pharmacol. 1995 Dec 7;293(4):301-8.
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