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(S,R,S)-AHPC-PEG2-NH2
CAS No. 2010159-60-9
(S,R,S)-AHPC-PEG2-NH2( VH032-PEG2-NH2 | VHL Ligand-Linker Conjugates 3 | E3 ligase Ligand-Linker Conjugates 6 Free Base )
Catalog No. M26953 CAS No. 2010159-60-9
(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 200MG | 376 | In Stock |
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Biological Information
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Product Name(S,R,S)-AHPC-PEG2-NH2
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NoteResearch use only, not for human use.
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Brief Description(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.
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Description(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsVH032-PEG2-NH2 | VHL Ligand-Linker Conjugates 3 | E3 ligase Ligand-Linker Conjugates 6 Free Base
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PathwayOthers
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TargetOther Targets
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Recptorσ1
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Research Area——
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Indication——
Chemical Information
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CAS Number2010159-60-9
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Formula Weight575.72
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Molecular FormulaC28H41N5O6S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Astragaloside(b)
Astragaloside may protect against brain contusion and neuronal apoptosis after TBI by attenuating microglia activation in male rats. Astragalosides-induced apoptosis in NB4 cells may be associated with down-regulation of the expression of BCL-2 and NF-κB finally the relative activity of caspase-3 activated.
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FGF basic (119-126) ...
bFGF (119-126) is a biological active peptide. (This peptide corresponds to human, bovine (119-126), mouse, rat (118-125) and Heparin-Binding Growth Factor 2 (118-125) residues of bFGF. It inhibits dimerization and activation of bFGF receptors.)
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[pSer2, pSer5, pSer7...
[pSer2, pSer5, pSer7]-CTD (TFA) is a substrate for CDK7(cyclin-dependent protein kinase), a phosphorylated polypeptide at ser2, ser5, and ser7 of RNA polymerase II carboxyl terminus (CTD).
